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PriMed Non-human Primate Model of Myocardial Ischemia

Myocardial ischemia is a heart condition caused by a temporary lack of oxygen-rich blood to the heart. More than 6 million Americans live with myocardial ischemia. 

Myocardial ischemia or infarction models are usually induced by left anterior descending (LAD) ligation-reperfusion. Clinically relevant models of ischemia or infarction are needed for novel treatment studies.

At PriMed Shines, our spontaneous myocardial ischemia model correlates well with the changes in MRI features and cardiac enzymes.

PriMed Posters and Publications

ADA 77th Scientific Sessions, San Diego

488-P: A Plant-Derived Drug Improves the Cardiac Function of Monkeys with Heart Failure and Type 2 Diabetes

ADA 76th Scientific Sessions, New Orleans

217-OR: Diffuse Myocardial Fibrosis Quantified by T1 Mapping at 3 T Increases in Early Diabetic Cardiomyopathy: A Preclinical Validation Study in Nonhuman Primates

ADA 75th Scientific Sessions, Boston

1840-P: Blood-Brain Barrier Permeability Increased in Rhesus Monkeys with Spontaneous T2DM: A Non-Invasive MRI Study

2393-PO: The Pathophysiology and Diagnosis for Spontaneous Type 2 Diabetes Mellitus Associated Diastolic Dysfunction in Rhesus Monkeys

More information about posterand publications                                                   

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